Obesity‐associated glomerular inflammation increases albuminuria without renal histological changes

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Obesity‐associated glomerular inflammation increases albuminuria without renal histological changes

1 Department of Nephrology, Kindai University Faculty of Medicine, Kindai University Nara Hospital, Nara, Japan 2 Department of Food Science and Nutrition, Faculty of Agriculture, Kindai University, Nara, Japan 3 Research Division, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA 4 Department of Applied Biological Chemistry, Graduate School of Agriculture, Kindai University, Nara...

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Diabetes mellitus is a progressive disease. Most investigators have focused on glomerular changes in diabetic kidney and non-glomerular alterations have been less attended. The present study has been conducted to find early non-glomerular histological changes in diabetic renal tissue. Twenty male Wistar rats weighting 200-250 g were used for the diabetic group. Diabetes mellitus was induced by ...

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The natural history of renal disease in Australian Aborigines. Part 1. Changes in albuminuria and glomerular filtration rate over time.

BACKGROUND The purpose of this study was to describe changes over time in albuminuria and glomerular filtration rate (GFR) in a cohort of Australian Aborigines from a community with high rates of renal disease and renal failure. METHODS Participants were 486 adult community members (20+ years at first exam) who were screened for renal disease and related factors on at least two occasions (mea...

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Changes in glomerular filtration rate after renal revascularization correlate with microvascular hemodynamics and inflammation in Swine renal artery stenosis.

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ژورنال

عنوان ژورنال: FEBS Open Bio

سال: 2018

ISSN: 2211-5463,2211-5463

DOI: 10.1002/2211-5463.12400